Sevoflurane: General anesthetics can potentiate the hypotensive effects of antihypertensive agents. Patients should be made aware of the possibility of syncopal and orthostatic symptoms, especially at the initiation of therapy, and to avoid driving or hazardous tasks for 12 hours after the first dose, after a dosage increase, and after interruption of therapy when treatment is resumed. They should be cautioned to avoid situations where injury could result should syncope occur during initiation of Terazosin capsule therapy. They should also be advised of the need to sit or lie down when symptoms of lowered blood pressure occur, although these symptoms are not always orthostatic, and to be careful when rising from a sitting or lying position. If dizziness, lightheadedness, or palpitations are bothersome they should be reported to the physician, so that dose adjustment can be considered. purchase generic skelaxin shop canada
In both studies, Tikosyn resulted in a dose-related increase in the number of patients maintained in NSR at all time periods and delayed the time of recurrence of sustained AF. Data pooled from both studies show that there is a positive relationship between the probability of staying in NSR, Tikosyn dose, and increase in QTc see in CLINICAL PHARMACOLOGY, Dose-Response and Concentration Response for Increase in QT Interval. Remember that terazosin will not shrink the size of your prostate but it does help to relieve the symptoms. Before initiating Tikosyn therapy, previous antiarrhythmic therapy should be withdrawn under careful monitoring for a minimum of three 3 plasma half-lives.
This variant of small pupil syndrome is characterized by the combination of a flaccid iris that billows in response to intraoperative irrigation currents, progressive intraoperative miosis despite preoperative dilation with standard mydriatic drugs, and potential prolapse of the iris toward the phacoemulsification incisions. It is possible that some side effects of terazosin may not have been reported. Extensively metabolized in the liver, a with minimal first-pass metabolism.
Amifostine: Patients receiving alpha-blockers should be closely monitored during amifostine infusions due to additive effects. Patients receiving amifostine at doses recommended for chemotherapy should have antihypertensive therapy interrupted 24 hours preceding administration of amifostine. If the antihypertensive cannot be stopped, patients should not receive amifostine. Carbinoxamine; Pseudoephedrine: The cardiovascular effects of pseudoephedrine may reduce the antihypertensive effects produced by alpha-blockers. Monitor blood pressure and heart rate. Dofetilide did not influence cardiac conduction velocity and sinus node function in a variety of studies in patients with or without structural heart disease.
Cod Liver Oil: Fish oil supplements may cause mild, dose-dependent reductions in systolic or diastolic blood pressure in untreated hypertensive patients. Relatively high doses of fish oil are required to produce any blood pressure lowering effect. Additive reductions in blood pressure may be seen when fish oils are used in a patient already taking antihypertensive agents. Terazosin helps relax the muscles in the prostate and the opening of the bladder. Guaifenesin; Pseudoephedrine: The cardiovascular effects of pseudoephedrine may reduce the antihypertensive effects produced by alpha-blockers. Monitor blood pressure and heart rate. Geriatric patients may be particularly susceptible to postural effects and other adverse effects. 9 See Geriatric Patients under Dosage and Administration. Are there other ways to treat constipation? Tikosyn dofetilide can cause serious ventricular arrhythmias, primarily Torsade de Pointes TdP type ventricular tachycardia, a polymorphic ventricular tachycardia associated with QT interval prolongation. QT interval prolongation is directly related to dofetilide plasma concentration. Factors such as reduced creatinine clearance or certain dofetilide drug interactions will increase dofetilide plasma concentration. The risk of TdP can be reduced by controlling the plasma concentration through adjustment of the initial dofetilide dose according to creatinine clearance and by monitoring the ECG for excessive increases in the QT interval. Lepor H. The emerging role of alpha antagonists in the therapy of benign prostatic hyperplasia. J Androl.
Female rats were unaffected. Geriatric patients may be more sensitive to the hypotensive and adverse effects dry mouth and drowsiness of terazosin. Monitor older adult patients closely. According to the Beers Criteria, terazosin is considered a potentially inappropriate medication PIM for use in geriatric patients and should be avoided as routine treatment of hypertension in this population due to the high risk of orthostatic hypotension and the availability of alternative agents with a superior benefit to risk profile. In addition, the Beers expert panel recommends avoiding terazosin in geriatric patients with syncope due to an increased risk of orthostatic hypotension or bradycardia, and also avoiding terazosin in elderly females with urinary incontinence, regardless of cause or type, because aggravation of incontinence may occur. The federal Omnibus Budget Reconciliation Act OBRA regulates medication use in residents of long-term care facilities LTCFs. According to the OBRA guidelines, antihypertensive regimens should be individualized to achieve the desired outcome while minimizing adverse effects. Antihypertensives may cause dizziness, postural hypotension, fatigue, and there is an increased risk for falls. Terazosin can cause significant hypotension and syncope during the first few doses; therefore, the dose should be administered at bedtime initially, and the drug slowly titrated as needed. There are many drug interactions that can potentiate the effects of antihypertensives. Some agents require a gradual taper to avoid adverse consequences caused by abrupt discontinuation. Ethinyl Estradiol; Norelgestromin: Estrogen-containing oral contraceptive may induce fluid retention and may increase blood pressure in some patients taking antihypertensive agents. Such patients should be monitored to confirm that the desired antihypertensive effect is being obtained. Ethinyl Estradiol; Ethynodiol Diacetate: Estrogen-containing oral contraceptive may induce fluid retention and may increase blood pressure in some patients taking antihypertensive agents. Such patients should be monitored to confirm that the desired antihypertensive effect is being obtained. You will start with a 1 mg dose of terazosin hydrochloride. Then the dose will be increased as your body gets used to the effect of the medication. What should I discuss with my healthcare provider before taking terazosin Hytrin? The concomitant use of verapamil or the cation transport system inhibitors cimetidine, trimethoprim alone or in combination with sulfamethoxazole or ketoconazole with Tikosyn is contraindicated see and as each of these drugs cause a substantial increase in dofetilide plasma concentrations. In addition, other known inhibitors of the renal cation transport system such as prochlorperazine, dolutegravir and megestrol should not be used in patients on Tikosyn. Dexchlorpheniramine; Dextromethorphan; Pseudoephedrine: The cardiovascular effects of pseudoephedrine may reduce the antihypertensive effects produced by alpha-blockers. Monitor blood pressure and heart rate. Yohimbine: Yohimbine can increase blood pressure and therefore can antagonize the therapeutic action of antihypertensive agents in general. Ethinyl Estradiol; Levonorgestrel; Folic Acid; Levomefolate: Estrogen-containing oral contraceptive may induce fluid retention and may increase blood pressure in some patients taking antihypertensive agents. Such patients should be monitored to confirm that the desired antihypertensive effect is being obtained. Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This drug may make you dizzy or drowsy. not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. You should avoid driving or hazardous tasks for 12 hours after the first dose, after your dose is increased, and when this medication is restarted after it has been stopped. Limit beverages. Cohen JD. Long-term efficacy and safety of terazosin alone and in combination with other antihypertensive agents. celebrex
NYHA Functional Class I or II. Approximately one-half had structural heart disease including ischemic heart disease, cardiomyopathies, and valvular disease and about one-half were hypertensive. A substantial proportion of patients were on concomitant therapy, including digoxin over 60% diuretics over 20% and ACE inhibitors over 30%. About 90% were on anticoagulants. Concomitant use of trimethoprim alone or in combination with sulfamethoxazole is contraindicated. Trimethoprim 160 mg in combination with 800 mg sulfamethoxazole co-administered BID with Tikosyn 500 mcg BID for 4 days has been shown to increase dofetilide AUC by 103% and C max by 93%. HernandezCano N, Herranz P, Lazaro TE, Mayor M, Casado M "Severe cutaneous reaction due to terazosin. Day 23 reflecting a steady state of dosing. A linear relationship between mean QTc increase and dofetilide dose was also seen in patients with renal impairment, in patients with ischemic heart disease, and in patients with supraventricular and ventricular arrhythmias. Patients were treated for at least one year. One study was in patients with moderate to severe 60% NYHA Class III or IV congestive heart failure DIAMOND CHF and the other was in patients with recent myocardial infarction DIAMOND MI of whom 40% had NYHA Class III or IV heart failure. Both groups were at relatively high risk of sudden death. The DIAMOND trials were intended to determine whether Tikosyn could reduce that risk. This risk is higher when taking your first dose. lechak.info famciclovir
In volunteers with varying degrees of renal impairment and patients with arrhythmias, the clearance of dofetilide decreases with decreasing creatinine clearance. As a result, and as seen in clinical studies, the half-life of dofetilide is longer in patients with lower creatinine clearances. Carbetapentane; Phenylephrine; Pyrilamine: Sympathomimetics can antagonize the effects of antihypertensives such as alpha-blockers when administered concomitantly. Acetaminophen; Chlorpheniramine; Dextromethorphan; Pseudoephedrine: The cardiovascular effects of pseudoephedrine may reduce the antihypertensive effects produced by alpha-blockers. Monitor blood pressure and heart rate. Tell your doctor or dentist that you take terazosin before you receive any medical or dental care, emergency care, or surgery including eye surgery. Torsade de Pointes is the only arrhythmia that showed a dose-response relationship to Tikosyn treatment. It did not occur in placebo treated patients. Ask your doctor before using terazosin together with ethanol. Using terazosin with ethanol can lower your blood pressure. This can cause dizziness or feeling like you might pass out, especially when getting up from a sitting or lying position. This may be more likely to occur when you first start taking either of these medications. You may need a dose adjustment or need your blood pressure checked more often if you take both medications. You may develop flushing, warmth or redness under your skin or tingly feeling after alcohol intake especially in you are of Asian descent and should be advised to avoid alcohol or limit your intake. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor. Pseudoephedrine: The cardiovascular effects of pseudoephedrine may reduce the antihypertensive effects produced by alpha-blockers. Monitor blood pressure and heart rate. Most people with do not feel sick. Tell your doctor if your remain high or increase. What other drugs will affect terazosin Hytrin? Concomitant use of HCTZ alone or in combination with triamterene is contraindicated. order injectable tamoxifen
Tikosyn than on placebo were: angina pectoris, anxiety, arthralgia, asthenia, atrial fibrillation, complications application, injection, incision, insertion, or device hypertension, pain, palpitation, peripheral edema, supraventricular tachycardia, sweating, urinary tract infection, ventricular tachycardia. Lowe FC "Safety assessment of terazosin in the treatment of patients with symptomatic benign prostatic hyperplasia - a combined analysis. Priapism reported rarely; may lead to permanent impotence if not treated promptly. 1 48 49 See Advice to Patients. The prevalence of adverse reactions has been ascertained from clinical trials conducted primarily in the United States. All adverse experiences events reported during these trials were recorded as adverse reactions. The prevalence rates presented below are based on combined data from fourteen placebo-controlled trials involving once-a-day administration of Terazosin, as monotherapy or in combination with other antihypertensive agents, at doses ranging from 1 to 40 mg. Table 3 summarizes those adverse experiences reported for patients in these trials where the prevalence rate in the Terazosin group was at least 5%, where the prevalence rate for the Terazosin group was at least 2% and was greater than the prevalence rate for the placebo group, or where the reaction is of particular interest. Ziprasidone: Ziprasidone is a moderate antagonist of alpha-1 receptors and may cause orthostatic hypotension with or without tachycardia, dizziness, or syncope. Additive hypotensive effects are possible if ziprasidone is used concurrently with antihypertensive agents. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. Drospirenone; Ethinyl Estradiol; Levomefolate: Estrogen-containing oral contraceptive may induce fluid retention and may increase blood pressure in some patients taking antihypertensive agents. Such patients should be monitored to confirm that the desired antihypertensive effect is being obtained. The dose may be slowly increased to achieve the desired blood pressure response. The usual recommended dose range is 1 mg to 5 mg administered once a day; however, some patients may benefit from doses as high as 20 mg per day. Doses over 20 mg do not appear to provide further blood pressure effect and doses over 40 mg have not been studied. Blood pressure should be monitored at the end of the dosing interval to be sure control is maintained throughout the interval. It may also be helpful to measure blood pressure 2 to 3 hours after dosing to see if the maximum and minimum responses are similar, and to evaluate symptoms such as dizziness or palpitations which can result from excessive hypotensive response. If response is substantially diminished at 24 hours an increased dose or use of a twice daily regimen can be considered. If Terazosin administration is discontinued for several days or longer, therapy should be reinstituted using the initial dosing regimen. In clinical trials, except for the initial dose, the dose was given in the morning. Alemtuzumab: Alemtuzumab may cause hypotension. Careful monitoring of blood pressure and hypotensive symptoms is recommended especially in patients with ischemic heart disease and in patients on antihypertensive agents. Tikosyn. Of these, 4 cases occurred within the first 3 days of dosing and 3 cases occurred between Day 4 and the conclusion of the study. What is hypertension high blood pressure? Constipation, diarrhea, dry mouth, dyspepsia, flatulence, vomiting. purchase now dimenhydrinate visa
Food and Drug Administration. Adults: approximately 12 hours. In the DIAMOND population, adverse events other than those related to the post-infarction and heart failure patient population were generally similar to those seen in the supraventricular arrhythmia groups. Trandolapril; Verapamil: The first-dose response acute postural hypotension of terazosin can be potentiated by coadministration with beta-blockers. The use of alpha-blockers with verapamil can lead to excessive hypotension; In addition, verapamil has been reported to increase the AUC and Cmax of prazosin and terazosin. Amphetamines: Amphetamines increase both systolic and diastolic blood pressure and may counteract the activity of some antihypertensive agents. Due to the risk of unopposed alpha-adrenergic activity, amphetamines should be used cautiously with beta-blockers. Increased blood pressure, bradycardia, or heart block may occur due to excessive alpha-adrenergic receptor stimulation. In particular, amphetamines can inhibit the antihypertensive response to guanadrel, an adrenergic antagonist that causes depletion of norepinephrine in the synapse. Close monitoring of blood pressure or the selection of alternative therapeutic agents may be needed. Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking terazosin, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Somberg JC. Terazosin: pharmacokinetics and the effect of age and dose on the incidence of adverse events.
RxList is part of the WebMD Health Network. The opinions expressed in the WebMD User Reviews are solely those of the User, who may or may not have medical or scientific training, and do not represent the opinions of WebMD. These member reviews have not been reviewed by a WebMD physician or any member of the WebMD editorial staff for accuracy, balance, objectivity, or any other purpose except for compliance with our Terms and Conditions. Chlorpheniramine; Pseudoephedrine: The cardiovascular effects of pseudoephedrine may reduce the antihypertensive effects produced by alpha-blockers. Monitor blood pressure and heart rate. Finasteride: Terazosin has been reported to increase peak concentrations of finasteride by 16% and AUC by 31% when the two agents are coadministered. The interaction is of minor importance. Tetracaine: Local anesthetics may cause additive hypotension in combination with antihypertensive agents. Use extreme caution with the concomitant use of tetracaine and antihypertensive agents. How should I store Tikosyn? Studies on terazosin have been done only in adult patients, and there is no specific information comparing use of terazosin in children with use in other age groups. Kirby RS, Coppinger SW, Corcoran MO et al. Prazosin in the treatment of prostatic obstruction. A placebo-controlled study. Br J Urol. Limited measurements of peak response 2 to 3 hours after dosing during chronic Terazosin administration indicate that it is greater than about twice the trough 24 hour response, suggesting some attenuation of response at 24 hours, presumably due to a fall in blood Terazosin concentrations at the end of the dose interval. AFl after drug-induced or electrical cardioversion. Black HR, Elliott WJ, Neaton JD et al. Baseline characteristics and elderly blood pressure control in the CONVINCE trial. Hypertension. Importance of informing clinicians of existing or contemplated concomitant therapy, including prescription and OTC drugs, as well as concomitant illnesses. Niacin; Simvastatin: Cutaneous vasodilation induced by niacin may become problematic if high-dose niacin is used concomitantly with other antihypertensive agents. This effect is of particular concern in the setting of acute myocardial infarction, unstable angina, or other acute hemodynamic compromise. Only 4% of 354 patients from a multicenter trial complained of general abdominal pain or diarrhea within the first 90 days of therapy. In the treatment of benign prostatic hypertrophy, terazosin blocks alpha1-adrenergic receptors present in the smooth muscle of the bladder neck and prostate, allowing the bladder neck and the prostate to relax. This causes less pressure on the urethra and increases urine flow. Terazosin appears to be more effective than finasteride Proscar for relieving symptoms associated with BPH. At first, 1 mg taken at bedtime. Then, 1 to 5 mg once a day. Patients should be advised about the possibility of priapism as a result of treatment with terazosin and other similar medications. Patients should know that this reaction to terazosin is extremely rare, but that if it is not brought to immediate medical attention, it can lead to permanent erectile dysfunction impotence. online terazosin information
May consider combined therapy with an α 1-adrenergic blocker and 5α-reductase inhibitor for men with bothersome moderate to severe BPH and demonstrable prostatic enlargement. 59 Has been more effective than therapy with either drug alone in preventing long-term BPH symptom progression. 59 Men at risk for BPH progression are most likely to benefit from combination therapy. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. Tikosyn for 1757 patient years. Take any laxative or bulking agent with plenty of water or other liquids. Respiratory system side effects have been limited to nasal congestion in 2% to 12% of patients. In addition to the use of the medicine your doctor has prescribed, treatment for your high blood pressure may include weight control and care in the types of foods you eat, especially foods high in sodium. Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet. Number of patients evaluated for QTc change: 478 Tikosyn, 167 placebo. Hytrin, and shortly after taking the drug during the first week of treatment. Post-marketing experience indicates that in rare instances patients may develop allergic reactions, including anaphylaxis, following administration of Terazosin hydrochloride. There have been reports of priapism and thrombocytopenia during post-marketing surveillance. Atrial fibrillation has been reported. Candida KAN di duh. Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. The prostate is a gland located below the bladder of men. It surrounds the urethra you-REETH-rah which is a tube that drains urine from the bladder. BPH is an enlargement of the prostate gland. The symptoms of BPH, however, can be caused by an increase in the tightness of muscles in the prostate. If the muscles inside the prostate tighten, they can squeeze the urethra and slow the flow of urine. This can lead to symptoms such as: What is BPH? If you are taking this drug for an enlarged prostate, it may take 2 to 4 weeks to see an improvement in your symptoms, and up to 6 weeks before you see the full benefit of this drug. Tell your doctor if your condition does not improve or if it worsens. It may take up to 6 weeks before your symptoms get better. quinine rebate
If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease. Chapple CR, Christmas TJ, Milroy EJ. A twelve-week placebo-controlled study of prazosin in the treatment of prostatic obstruction. Urol Int. Enflurane: General anesthetics can potentiate the hypotensive effects of antihypertensive agents. Your doctor will start this medication at a low dose and gradually increase your dose. Any time your dose is increased or if you restart treatment after you have stopped it, take your first dose at bedtime unless otherwise directed to lessen the risk of injury related to dizziness or fainting. Also during these times, avoid situations where you may be injured if you faint. Azelaic Acid; Copper; Folic Acid; Nicotinamide; Pyridoxine; Zinc: Cutaneous vasodilation induced by niacin may become problematic if high-dose niacin is used concomitantly with other antihypertensive agents. Cutaneous vasodilation induced by niacin may become problematic if high-dose niacin is used concomitantly with other antihypertensive agents. This effect is of particular concern in the setting of acute myocardial infarction, unstable angina, or other acute hemodynamic compromise. Store at room temperature between 59 and 77 degrees F 15-25 degrees C away from light and moisture. not store in the bathroom. Keep all medicines away from children and pets. The drug is 90 to 94% bound to plasma proteins and binding is constant over the clinically observed concentration range. Approximately 10% of an orally administered dose is excreted as parent drug in the urine and approximately 20% is excreted in the feces. The remainder is eliminated as metabolites. Impaired renal function had no significant effect on the elimination of Terazosin, and dosage adjustment of Terazosin to compensate for the drug removal during hemodialysis approximately 10% does not appear to be necessary. Overall, approximately 40% of the administered dose is excreted in the urine and approximately 60% in the feces. The disposition of the compound in animals is qualitatively similar to that in man. Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label. Highest dose 10 mg shown. Phentermine; Topiramate: Sympathomimetics can antagonize the effects of antihypertensives such as alpha-blockers when administered concomitantly. If you miss your doses for several days in a row, contact your doctor before restarting the medication. You may need a lower dose. Should overdosage of Terazosin capsules lead to hypotension, support of the cardiovascular system is of first importance. Restoration of blood pressure and normalization of heart rate may be accomplished by keeping the patient in the supine position. If this measure is inadequate, shock should first be treated with volume expanders. If necessary, vasopressors should then be used and renal function should be monitored and supported as needed. Laboratory data indicate that Terazosin capsules are 90-94% protein bound; therefore, dialysis may not be of benefit. Both studies randomized patients to placebo or to doses of Tikosyn 125 mcg, 250 mcg, 500 mcg, or in one study a comparator drug, given twice a day these doses were lowered based on calculated creatinine clearance and, in one of the studies, for QT interval or QTc. QD was co-administered with Tikosyn 500 mcg BID for 5 days following 2 days of diuretic use at half dose. In patients receiving HCTZ alone, dofetilide AUC increased by 27% and C max by 21%. However, the pharmacodynamic effect increased by 197% QTc increase over time and by 95% maximum QTc increase. In patients receiving HCTZ in combination with triamterene, dofetilide AUC increased by 30% and C max by 16%. However, the pharmacodynamic effect increased by 190% QTc increase over time and by 84% maximum QTc increase. The pharmacodynamic effects can be explained by a combination of the increase in dofetilide exposure and the reductions in serum potassium. In the DIAMOND trials, 1252 patients were treated with Tikosyn and diuretics concomitantly, of whom 493 died compared to 508 deaths among the 1248 patients receiving placebo and diuretics. neurontin
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Acetaminophen; Dextromethorphan; Guaifenesin; Phenylephrine: Sympathomimetics can antagonize the effects of antihypertensives such as alpha-blockers when administered concomitantly. This medication passes into breast milk. Consult your doctor before breast-feeding. Acute conversion rates are shown in Table 1 for randomized doses doses were adjusted for calculated creatinine clearance and, in Study 1, for QT interval or QTc. grifulvin price coupon
During the period of in-hospital initiation of dosing, 23% of patients in Studies 1 and 2 had their dose adjusted downward on the basis of their calculated creatinine clearance, and 3% had their dose down-titrated due to increased QT interval or QTc. Increased QT interval or QTc led to discontinuation of therapy in 3% of patients. Tell your doctor if you have any side effects that bother you or do not go away. Ruoff G. Comparative trials of terazosin with other antihypertensive agents. Am J Med. Tikosyn can be taken with or without food. If you are taking this medication for high blood pressure, it is important to continue taking this medication even if you feel well. Most people with high blood pressure do not feel sick. Tell your doctor if your blood pressure readings remain high or increase.
Kyncl JJ. Pharmacology of terazosin. Am J Med. TABLE 3. Adverse Reactions During Placebo-Controlled Trials Hypertension Includes weakness, tiredness, lassitude, and fatigue. If any of these effects persist or worsen, notify your doctor or promptly. In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. Use this medication regularly to get the most benefit from it. To help you remember, use it at the same times each day.
Read the patient instruction sheet that comes with this product before you start using desmopressin and each time you get a refill. If you have any questions, consult your doctor or pharmacist. Take this medication by mouth with or without food as directed by your doctor, usually once daily at bedtime. Keep Tikosyn and all medicines out of the reach of children. Our Hytrin terazosin hydrochloride Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. Tikosyn. The majority of cases 76% occurred within the first 3 days of dosing.